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- W2363747774 abstract "Objective To investigate and analysis the clinical and pathological features of primary glomerulonephritis with crescent formation. Methods 84 primary glomerulonephritis patients with crescent formation were retrospectively analyzed. There were 37 male cases and 47 female cases; Mean age was( 36. 13 ± 4. 56) years old. The patients were divided into two groups according to the percentage of crescent formation: group A( 10%),group B( 10%). The clinical manifestation,renal biopsy pathology types,and prognosis of disease were analyzed. Results Hematuria: there were 15 patients in group A and 27 cases in group B; Proteinuria: in group A,there were 20 cases with urine protein 1. 0 g·d- 1,and 19 cases with urine protein 1. 0 g·d- 1; in group B,there were 13 cases with urine protein 1. 0 g·d- 1,and 32 cases with urine protein 1. 0 g·d- 1; Renal function: there were 34 cases in group A and 29 cases in group B regarding serum creatinine 133 umol·L- 1; there were 5 cases in group A and 16 cases in group B regarding serum creatinine 133 umol·L- 1. there were 16 patients with acute renal failure,2 cases in group A and 14 cases in group B; High blood pressure: A total of 56 patients with hypertension,24 cases in group A and 32 cases in group B. Renal pathology types: there were 75 cases with IgA nephropathy,3 cases with membranous nephropathy,2 cases with type 2 primary crescent nephritis( RPGN),1 case with membrane glomerulonephritis,1 case with focal sclerosing glomerulonephritis,1 case with focal proliferative glomerulonephritis,and 1 case with focal segmental glomerulosclerosis. Hematuria,proteinuria,and the serum levels of serum creatinine between the two groups was statistically difference( P 0. 05),while the incidence of hypertension showed no statistical difference( P 0. 05). Conclusion The renal pathology feature of primary glomerulonephritis are of variety. If accompanied by crescent formation,deteriorating is fast and prognosis is poor. Renal biopsy is needed as soon as possible to definite pathological diagnosis,and early treatment can improve prognosis." @default.
- W2363747774 created "2016-06-24" @default.
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- W2363747774 date "2014-01-01" @default.
- W2363747774 modified "2023-09-22" @default.
- W2363747774 title "The clinical and pathological analysis of primary glomerulonephritis with crescent formation" @default.
- W2363747774 hasPublicationYear "2014" @default.
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