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- W2363757536 abstract "In order to study the effect of microRNA-152(miR-152)on milk protein synthesis in dairy cow mammary epithelial cells,liposome transfection was used to change the expression of miR-152in bovine mammary epithelial cells.The influence of miR-152on the cell proliferation and lactation was detected using Real-time PCR,Western blotting,cell viability analysis and other techniques.Results indicated that when miR-152was inhibited,SOCS3 protein expression was increased,signaling pathway factors p-STAT5,p-mTOR,S6K1 and cyclinD1protein expression were decreased,cell proliferation was decreased,β-casein secretion was decreased.The results suggested that miR-152probably regulated bovine mammary epithelial cells by suppressing expression of SOCS3.And miR-152could increase milk protein synthesis and cells proliferation by regulating signal transductions of p-STAT5,p-mTOR,S6K1 and cyclinD1in mammary epithelial cells." @default.
- W2363757536 created "2016-06-24" @default.
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- W2363757536 date "2014-01-01" @default.
- W2363757536 modified "2023-09-22" @default.
- W2363757536 title "Effects of microRNA-152 on Milk Protein Synthesis in Bovine Mammary Epithelial Cells" @default.
- W2363757536 hasPublicationYear "2014" @default.
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