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- W236377509 abstract "Publisher Summary This chapter discusses the relationship between carcinogenicity, and the physical and the chemical properties of angular benzacridines. It explains that the benz[c]acridine series is richer in carcinogenic compounds than the benz[a]acridine series and that a relationship between the carcinogenicity and the charge of the compound seems to exist, but this last point deserves further study to be more precise. For this, better methods of calculation are established. It is also highly desirable that a theory that is able to interpret all physical data for benzacridines satisfactorily and simultaneously is worked out. It is only in this case that the values of the calculated charges are fully trusted. This chapter concludes that the systematic study carried out on the angular benzacridines has considerably increased the number of known carcinogenic substances, suggested theories relating carcinogenicity to the electronic density, and submitted these theories to the test of chemical and biological experiment. In order to do this, cooperation of different disciplines has been organized, as distant from one another as mathematics and quantum mechanics are from cancer research." @default.
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- W236377509 date "1956-01-01" @default.
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- W236377509 title "The Relation between Carcinogenic Activity and the Physical and Chemical Properties of Angular Benzacridines" @default.
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- W236377509 doi "https://doi.org/10.1016/s0065-230x(08)60727-7" @default.
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