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- W2363778441 abstract "Objective To establish rat model of brain stem glioma for MRI study.Materials and Methods Fischer 344 rats were inoculated with F98 glioma cells in brain stem by stereotaxic procedure. MRI scanning and pathology examination were performed to observed the tumor growth on 6、8、10、12、14 d after inoculation respectively and their survival was also anlayzed.Results After inoculation, tumors were found in all rats by MRI as early as 6 days. Most of rats died on 14 d after inoculation. The size of tumor increased as the inoculation time lengthen. The tumor volume measured by MRI was larger than actual size by autopsy, but correlated positively (r=0.94, P0.01). The tumor had pathological features of glioma.Conclusion The animal model of glioma with high and rapid tumorigenesis is an ideal model for MRI study characterized by prospectability and repeatability, and its perfect study duration is between 10～14 days after inoculation of tumor cells." @default.
- W2363778441 created "2016-06-24" @default.
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- W2363778441 date "2005-01-01" @default.
- W2363778441 modified "2023-09-24" @default.
- W2363778441 title "The Establishment of Rat Glioma Model of Brain Stem for MRI Study" @default.
- W2363778441 hasPublicationYear "2005" @default.
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