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- W2363780226 abstract "Objective To establish a HPLC method for the content determination of Pseudoephedrine hydrochloride,Chlorphenamine maleate and Dextromethorphan hydrobromide in Pseudoephedrine hydrochloride chlorphenamine maleate and dextromethorphan hydrobromide solution.Method The separation was performed on HYPERSIL C_(18) column(4.6 mm×200 mm,0.5 μm),the mobile phase was 0.0025 hexanesulfonic acid sodium salt methanolic solution-water(1.5% triethylamine)(53∶47),adjusted with phosphoric acid to pH3.0.The detection wavelength was at 205 nm,the flow rate was 1.0 ml·min~(-1). Result The linearity is in range of 5.48~274 μg·ml~(-1)(r=0.99997,n=5)of Pseudoephedrine hydrochloride,0.43~21.4 μg·ml~(-1)(r=1.0000,n=5)of Chlorphenamine maleate,1.94~96.8 μg·ml~(-1)(r=0.99998,n=5)of dextromethorphan hydrobromide,respectively.Conclusion This method is simple,rapid,accurate and reproducible,and it's suitable for content determination of Rseudoephedrine hydrochloride,Chlorphenamine maleate and Dextromethorphan hydrobromide in Pseudoephedrine hydrochloride Chlorphenamine maleate and dextromethorphan hydrobromide solution." @default.
- W2363780226 created "2016-06-24" @default.
- W2363780226 creator A5088817458 @default.
- W2363780226 date "2006-01-01" @default.
- W2363780226 modified "2023-09-25" @default.
- W2363780226 title "Determination of Pseudoephedrine Hydrochloride,Chlorphenamine Maleate and Dextromethorphan Hydrobromide Together in Pseudoephedrine Hydrochloride Chlorphenamine Maleate and Dextromethorphan Hydrobromide Solution by HPLC" @default.
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