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- W2363786274 abstract "Objective] To explore the protective effects of zinc pre-supplement on decreasing the activities of alkaline phosphatase(ALP)and superoxide dismutase(SOD)in liver and serum of rats treated with cadmium. [Methods] Thirty-six Wistar rats were randomly divided into six groups:blank control group,zinc pre-supplement control group,cadmium low dose group(0.5 mgCd/kg),low dose cadmium with zinc pre-supplement group,cadmium high dose group(2 mgCd/kg) and high dose cadmium with zinc pre-supplement group.Every group was given common feed.Zinc pre-supplement group was given additional zinc for 6 days.Then the activities of ALP and SOD were determined 24 hours after cadmium was injected intraperitoneally at the different doses. [Results] The activities of SOD in liver in control group is 77.963±12.915 NU/mg Pr and it decreased to(60.021±9.481) NU/mg Pr in cadmium high dose group(P0.05).The activities of ALP in liver in control group is(13.066±4.198) King Unit/L and it decreased to 1.939±1.056 King Unit/L in cadmium high dose group(P0.05).The activities of ALP in serum in control group is(31.260±2.459) King Unit/L and it decreased to (17.677±3.704) King Unit/L in cadmium high dose group(P0.05).In the groups of zinc pre-supplement and cadmium injection SOD and ALP activities increased in different degree. [Conclusion] Cadmium could inhibit the activities of ALP and SOD in liver,and the activities of ALP in serum respectively.Zinc pre-supplement to rats could antagonize these Cd effects in certain degree." @default.
- W2363786274 created "2016-06-24" @default.
- W2363786274 creator A5009261647 @default.
- W2363786274 date "2005-01-01" @default.
- W2363786274 modified "2023-09-23" @default.
- W2363786274 title "The Protective Effects of Zinc Pre-supplement on Decreasing the Activities of ALP and SOD in Liver and Serum of Rats,Treated with Cadmium" @default.
- W2363786274 hasPublicationYear "2005" @default.
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