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- W2363815030 abstract "[Objective] To characterize the effects of 17β-estrodiol(17β-E2) on the expression of IL-6, IL-11 and NF-κB in human osteoblast line MG-63. [Methods] The expression of IL-6 was tested by RT-PCR, Northern blot and Western Blot. The expression of IL-11 was tested by RT-PCR and NF-κB was tested by Western Blot. [Result] 17β-E2 can down-regulate the expression of IL-6 mRNA and protein in MG-63 cells. 17β-E2 can down-regulate the expression of IL-11 mRNA, protein and NF-κB protein in MG-63 cells. [Conclusion] The expression of NF-κB, IL-6 and IL-11 in MG-63 cells can be suppressed by 17β-E2, and this may support the estrogen replacement therapy in postmenopausal women." @default.
- W2363815030 created "2016-06-24" @default.
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- W2363815030 date "2005-01-01" @default.
- W2363815030 modified "2023-09-26" @default.
- W2363815030 title "Effects of 17 β-estrodiol on the expression of IL-6, IL-11 and NF-κB in human osteoblast line MG-63" @default.
- W2363815030 hasPublicationYear "2005" @default.
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