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- W2363842189 abstract "Objective To study the optimal method of preparing the rabbit acellular dermal matrix ( ADM). Methods To prepare the rabbit ADM, we treated rabbit skin with three different methods ( hyperosmotic NaCl solution, dispase II ,or thermolysin) to remove the epidermis and excluded the cellular components in the dermis with detergent solution ( SDS). The characters of the ADMs were examined his-topathologically. Results Histopathological examination by light microscopy and electron microscopy showed the rabbit ADM prepared by dispase II - SDS or thermolysin - SDS was a kind of matrix with an intact basement membrane and normal structure of collagen without any epidermis and cellular components. However, the matrix prepared by the hyperosmotic NaCl solution had little epidermis and cell debris in the dermis as compared to the two former detergents. Conclusion The rabbit ADM prepared by dispase II -SDS, or thermolysin - SDS meets the standard requitement." @default.
- W2363842189 created "2016-06-24" @default.
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- W2363842189 date "2003-01-01" @default.
- W2363842189 modified "2023-09-25" @default.
- W2363842189 title "The Preparation of the Rabbit Acellular Dermal Matrix" @default.
- W2363842189 hasPublicationYear "2003" @default.
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