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- W2363888253 abstract "Multidrug resistance is now recognized as one of the common causes for the failure of cancer chemotherapy. Classic MDR is associated with the overexpression of p-glycoprotein(p-gp), resulting in increased efflux of chemotherapeutic agents from cancer cells and decrement of the therapeutic effect. Therefore, effective inhibiting the activity of p-glycoprotein can be used to reverse the MDR of tumor cells. This article introduces the development of the p-glycoprotein inhibitors, characteristics of 1～3 generation of p-glycoprotein inhibitors, and the clinical trials of the second and third generation of p-glycoprotein inhibitors." @default.
- W2363888253 created "2016-06-24" @default.
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- W2363888253 date "2004-01-01" @default.
- W2363888253 modified "2023-09-25" @default.
- W2363888253 title "Advances in Inhibitor of P-Glycoprotein" @default.
- W2363888253 hasPublicationYear "2004" @default.
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