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- W2363904534 abstract "Objective To compare and analyze the dose distribution and protection for organ at risk(OAR)of three-dimensional conformal radiotherapy(3D-CRT),intensity-modulated radiation therapy(IMRT)and volumetric modulated arc therapy(VMAT)in the postoperative radiotherapy of cervical carcinoma,to provide a more effective and safe mode clinically.Methods 3D-CRT,IMRT and VMAT plans were generated in 10 consecutive patients with cervical cance who underwent srugery in Peking University Third Hospital during 2013.The three techniques were then compared using dose volume histogram(DVH)analysis,the conformal index(CI),homogeneity index(HI)and dose of OAR.Results Compared with CRT,the CI of IMRT and VMAT were both improved,which showed 0.462,0.855 and 0.875,respectively,and VMAT was better than IMRT(P0.05,t=-2.189)statistically.While the HI of the three techniques were 1.084,1.063 and 1.046,respectively,and VMAT was poorer than IMRT(P0.05,t=5.127).As to the dose delivered to OAR,CRT was more serious than IMRT and VMAT.For low dose rate volume,as to the V10,V20 of small intestine,colorectum,bladder and bone marrow IMRT carried less doses than VMAT(P0.05).For high dose rate volume,as to V40 and V50,IMRT technique carried less doses reaching rectum and bladder.Other OARs,such as small intestine,colon,femoral heads and bone marrow seemed the same as IMRT and VMAT(P0.05).Conclusions All the three techniques could covered the PTV correctly,IMRT and VMAT are superior than CRT in many indexes.Compared with VMAT,IMRT has advantage in HI while disadvantage in CI.For OARs,both IMRT and VMAT gained special characteristics as to low and high dose rate,which in turn shows differences in clinic." @default.
- W2363904534 created "2016-06-24" @default.
- W2363904534 creator A5055858494 @default.
- W2363904534 date "2015-01-01" @default.
- W2363904534 modified "2023-09-26" @default.
- W2363904534 title "Dosimetric study comparing 3D-CRT,IMRT and VMAT in postoperative radiotherapy of cervical carcinoma" @default.
- W2363904534 hasPublicationYear "2015" @default.
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