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- W2364015181 abstract "Objective: To reveal the relationship between the effect of the anti-tumor of the pachyman polysaccharides(PPS) modified by chemical technique and the apoptosis related gene products,such as Bax,Bcl-2 and Fas.Methods: ① Twenty BALB/c mice at the age of 7-8 weeks,which were inoculated with Sarcoma 180 cells(5×10~(6) cells/ml) at the hypodermis of the back,were assigned into two groups randomly and equally: the group treated by PPS and the control group treated by phosphoric acid buffer solution.All mice were injected intraperitoneally once per day for seven days before were killed at the ninth day and their tumor tissues were harvested.② Fas,Bcl-2 and Bax in tumor tissues were assayed by SP.Results: There were significant differences between the two groups in these indices,including Fas,Bcl-2 and Bax expression.Conclusion: The PPS modified by chemical technique can induce the apoptosis of the Sarcoma 180 tumor cells of mice." @default.
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- W2364015181 date "2007-01-01" @default.
- W2364015181 modified "2023-09-26" @default.
- W2364015181 title "Immunohistochemical Observation on the Anti-tumor Effect of the Pachyman Polysaccharides Modified by Chemical Technique" @default.
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