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- W2364017166 abstract "Objective To investigate the relationship of the expressions of chemokine receptor CXCR4 and vascular endothelial growth factor C (VEGF-C) with tumor metastasis in human gastric cancer.Methods Immuohistochemistry was used to detect the expressions of CXCR4 and VEGF-C in 207 samples of human gastric cancer.The relationship between CXCR4 and VEGF-C expressions and the clinicpatho-logical diameters was statistically analyzed. Results The positive rate of CXCR4 expression with lymph node metastasis was higher than that without lymph node metastasis(54.2% vs 25.6%,P0.01).The positive rate of VEGF-C expression with lymph node metastasis was higher than that without lymph node metastasis(48.2% vs 21.8%,P0.01). The positive rate of CXCR4 expression with peritoneal metastasis was higher than that without peritoneal metastasis(78.4% vs 26.5%,P0.01). But the positive rate of VEGF-C expression with peritoneal metastasis was closed to that without peritoneal metastasis(27.0% vs 33.5%,P0.05). The positive expression of CXCR4 was consistent with the positive expression of VEGF-C,and the expression levels of CXCR4 and VEGF-C were closely correlated with lymph node metastasis, but not with,histological type,cellular differentiation and invasion depth,age,sex,tumor size.Conclusion CXCR4 and VEGF-C expressions may become predictors for the metastasis and recurrence of gastric cancer." @default.
- W2364017166 created "2016-06-24" @default.
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- W2364017166 date "2007-01-01" @default.
- W2364017166 modified "2023-09-25" @default.
- W2364017166 title "Correlation of CXCR4 and VEGF-C expressions with metastasis in human gastric cancer" @default.
- W2364017166 hasPublicationYear "2007" @default.
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