Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364019881> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2364019881 abstract "Objectives: To explore the relationship betweenquantitative Treponema pallidum DNA (TP-DNA) PCR testingand the Toludine Red Unheated Serum Test (TRUST) inpatients with syphilis before and after treatment, and evaluatethe clinical value of quantitative TP-DNA testing in thediagnosis and treatment evaluation of syphilis. Methods: 29 patients with primary (12 cases) or secondary(17 cases) syphilis, who met the criteria set for this study wererecruited as subjects. All patients were treated with 2.4 millionunits benzathine penicillin IM weekly for 3 weeks.Quantitative tests of TP-DNA in the patients' plasma wereperformed using FQ-PCR before and after the treatment.Serologic tests including TRUST and TPPA were alsoperformed. Results: Before the treatment, 9 out of 12 primary syphilispatients (75%) and all secondary syphilis patients (17/17)tested positive for Treponema pallidum (TP) by TP-DNAtesting. The average quantitative test values of TP-DNA inprimary and secondary syphilis patients were (3.38±2.34)×10~4and (5.73±1.33)×10~6 copies/ml, respectively. After threemonths of treatment, 1 of the 9 primary and 5 out of 17secondary syphilis patients were positive upon TP-DNAtesting, respectively. The average quantities of TP-DNA were2.01×10~2 copies/ml in primary and 5.87×10~2 copies/ml insecondary syphilis patients with positive TRUST and TP-DNAtests, and 3.09×10~2 copies/ml for those with negative TRUSTrespectively. After nine months of treatment, all the primaryand secondary syphilis patients were negative upon TP-DNAtesting, while all primary and 14 of 17 (82.35%) secondarysyphilis patients showed negative TRUST results. Conclusion: That the results of TP-DNA tests are notconsistent with those or TRUST before and after treatmentindicates that quantitative TP-DNA testing may have valuableclinical significance in the early diagnosis and evaluation oftreatment regimens for syphilis." @default.
- W2364019881 created "2016-06-24" @default.
- W2364019881 creator A5068356313 @default.
- W2364019881 date "2002-01-01" @default.
- W2364019881 modified "2023-09-23" @default.
- W2364019881 title "A Preliminary Study of The Value of Quantitative Testing of TP-DNA In The Treatment of Patients with Syphilis" @default.
- W2364019881 hasPublicationYear "2002" @default.
- W2364019881 type Work @default.
- W2364019881 sameAs 2364019881 @default.
- W2364019881 citedByCount "0" @default.
- W2364019881 crossrefType "journal-article" @default.
- W2364019881 hasAuthorship W2364019881A5068356313 @default.
- W2364019881 hasConcept C126322002 @default.
- W2364019881 hasConcept C159654299 @default.
- W2364019881 hasConcept C174802600 @default.
- W2364019881 hasConcept C203014093 @default.
- W2364019881 hasConcept C2776983459 @default.
- W2364019881 hasConcept C2780187896 @default.
- W2364019881 hasConcept C2908682542 @default.
- W2364019881 hasConcept C2910147798 @default.
- W2364019881 hasConcept C3013748606 @default.
- W2364019881 hasConcept C3018810166 @default.
- W2364019881 hasConcept C45189115 @default.
- W2364019881 hasConcept C501593827 @default.
- W2364019881 hasConcept C71924100 @default.
- W2364019881 hasConcept C86803240 @default.
- W2364019881 hasConcept C89423630 @default.
- W2364019881 hasConcept C90924648 @default.
- W2364019881 hasConceptScore W2364019881C126322002 @default.
- W2364019881 hasConceptScore W2364019881C159654299 @default.
- W2364019881 hasConceptScore W2364019881C174802600 @default.
- W2364019881 hasConceptScore W2364019881C203014093 @default.
- W2364019881 hasConceptScore W2364019881C2776983459 @default.
- W2364019881 hasConceptScore W2364019881C2780187896 @default.
- W2364019881 hasConceptScore W2364019881C2908682542 @default.
- W2364019881 hasConceptScore W2364019881C2910147798 @default.
- W2364019881 hasConceptScore W2364019881C3013748606 @default.
- W2364019881 hasConceptScore W2364019881C3018810166 @default.
- W2364019881 hasConceptScore W2364019881C45189115 @default.
- W2364019881 hasConceptScore W2364019881C501593827 @default.
- W2364019881 hasConceptScore W2364019881C71924100 @default.
- W2364019881 hasConceptScore W2364019881C86803240 @default.
- W2364019881 hasConceptScore W2364019881C89423630 @default.
- W2364019881 hasConceptScore W2364019881C90924648 @default.
- W2364019881 hasOpenAccess W2364019881 @default.
- W2364019881 hasRelatedWork W118508719 @default.
- W2364019881 hasRelatedWork W157639244 @default.
- W2364019881 hasRelatedWork W1999613953 @default.
- W2364019881 hasRelatedWork W2015960220 @default.
- W2364019881 hasRelatedWork W2034385430 @default.
- W2364019881 hasRelatedWork W2071216692 @default.
- W2364019881 hasRelatedWork W2116866431 @default.
- W2364019881 hasRelatedWork W2133883093 @default.
- W2364019881 hasRelatedWork W2351870217 @default.
- W2364019881 hasRelatedWork W2356234314 @default.
- W2364019881 hasRelatedWork W2368360969 @default.
- W2364019881 hasRelatedWork W2372049063 @default.
- W2364019881 hasRelatedWork W2378617179 @default.
- W2364019881 hasRelatedWork W2380148530 @default.
- W2364019881 hasRelatedWork W2389180128 @default.
- W2364019881 hasRelatedWork W2392212627 @default.
- W2364019881 hasRelatedWork W2756089982 @default.
- W2364019881 hasRelatedWork W2972005380 @default.
- W2364019881 hasRelatedWork W3023536683 @default.
- W2364019881 hasRelatedWork W3031256877 @default.
- W2364019881 isParatext "false" @default.
- W2364019881 isRetracted "false" @default.
- W2364019881 magId "2364019881" @default.
- W2364019881 workType "article" @default.