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- W2364031401 abstract "Objective To investigate the anti-inflammation and anti-atherosclerosis effects of rosiglitazone.Methods Type 2 diabetic patients with coronary artery disease were randomly devided into two groups,with or without rosiglitazone treatment.The serum MMP-9 and high-sensitivity C-reactive protein were determined with ELISA to observe the differences after treatment between the groups.Results The serum MMP-9 and high-sensitivity C-reactive protein levels after rosiglitazone treatment for 2 weeks decreaced compared to the baseline.However the changes of fasting plasma glucose in the two groups had no difference.The serum MMP-9 and high-sensitivity C-reactive protein levels were respectively after rosiglitazone treatment for 12 weeks decreaced significantly compared to that for 2 weeks.Conclusion Rosiglitazone has anti-inflammative and anti-atherosclerotic effects independent of the lowering blood glucose.And the lowering blood glucose and anti-atherosclerotic effects are depended on time in the periord." @default.
- W2364031401 created "2016-06-24" @default.
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- W2364031401 date "2009-01-01" @default.
- W2364031401 modified "2023-09-26" @default.
- W2364031401 title "Effect of rosiglitazone treatment on MMP-9 and high-sensitivity C-reactive protein in the patients with type 2 diabetes mellitus and coronary artery disease" @default.
- W2364031401 hasPublicationYear "2009" @default.
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