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- W2364034887 abstract "Objective:To evaluate the value that diagnosis renal tubular damage by colloidal gold immunochromatography assay of retinol-binding protein(RBP).Methods:Retinol-binding protein kit(colloidal gold immunochromatography) produced by Shanghai bionano Biotechnology Co.,Ltd.and RBP content assay kit(ELISA) produced by Shanghai Sun biotechnology Co.,Ltd.Were selected,comparative tests were used to detect urine samples which were divided into the case group and control group.To ELISA,if concentration is equal or greater than 300 ng mL-1,the result is positive,while low than 300 ng mL-1 will be negative;Coloration of test line means positive wile has no color means negative.Consistency of two detection methods will be analysed by Kappa consistency test,clinical diagnosis is treated as the standard which can help us to calculate the diagnostic sensitivity and specificity of colloidal gold immunochromatography assay.Results:The two detection methods,diagnostic consistency(No.1 hospital:K = 0.9070,95% CI:0.8277~0.9863,P 0.01;No.6 hospital:K = 0.9391,95% CI:0.8714~ 1.000,P 0.01).The sensitivity and specificity of the colloidal gold immunochromatography assay for diagnosis renal tubular damage,No.1 hospital:sensitivity = 100%,exact 95% CI:92.45%~ 100.00%;specificity = 91.80%,exact 95% CI:81.90%~ 97.28%;No.6 hospitals:sensitivity = 100%,exact 95% CI:92.45% to 100.00%;specificity = 91.80%,exact 95% CI:81.90%~ 97.28%.Conclusion:Colloidal gold immunochromatography assay of retinol-binding protein has a great value for the diagnosis of renal tubular injury." @default.
- W2364034887 created "2016-06-24" @default.
- W2364034887 creator A5030908494 @default.
- W2364034887 date "2012-01-01" @default.
- W2364034887 modified "2023-09-23" @default.
- W2364034887 title "The Diagnostic Value of RBP Colloidal Gold Assay on Renal Tubular Dysfunction" @default.
- W2364034887 hasPublicationYear "2012" @default.
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