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- W2364069891 abstract "Objective To explore the clinical application value of plasm endothelin-1 and magnesium using receiver operating characteristic(ROC)curve in patients with diabetic retinopathy,and to find out the high risk patients with type 2 diabetes mellitus.Methods Prospective investigation was used.The levels of plasm endothelin-1 and magnesium were measured in 240 cases with type 2 diabetes mellitus(96 cases with retinopathy and 144 cases without retinopathy as control).The diagnostic standard was identified by ocular fundus examination and fundus fluorescein angiography.ROC curve was used to assess their value in diagnosis of diabetic retinopathy.Results As the diadynamic criteria in the type 2 diabetes mellitus patients complicated with retinopathy,the under-curve area of plasm endothelin-1 were 0.737,the under-curve area of magnesium were 0.633.The positive rate could be elevated significantly in patients with diabetic retinopathy when plasm endothelin-1 and magnesium were simultaneously detected.Using the parallel test,the sensitivity was 92.39%,the specificity was 25.00%;Using the serial test,the sensitivity was 52.39%,the specificity was 76.10%.Conclusion The endothelin-1 and magnesium play a important role in the development and progression of diabetic retinopathy.Therefore,the detection of endothelin-1 and magnesium may be used to screen the high-risk group with diabetic retinopathy in type 2 diabetes mellitus." @default.
- W2364069891 created "2016-06-24" @default.
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- W2364069891 date "2007-01-01" @default.
- W2364069891 modified "2023-09-24" @default.
- W2364069891 title "Evaluation of plasm endothelin-1 and magnesium in diabetic retinopathy using receiver operating characteristic curve" @default.
- W2364069891 hasPublicationYear "2007" @default.
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