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- W2364084150 abstract "Objective To investigate high risk human papillomavirus(HPV)infection and cytological test conditions among women with gynecological-surgery in Haiyang city,Shandong Province.Methods From January 2009 to December 2009,a total of 4267 women with gynecological-surgery were screened by combining high risk HPV DNA test(hybrid capture Ⅱ,HC-Ⅱ)and Thin-prep cytological test(TCT).Diagnostic criteria for cervical cytopathology was used the 2001 Bethesda system.The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Affiliated Haiyang People's Hospital,Qingdao University Medical College.Informed consent was obtained from all participants.Results ①The total positive infection rate of high risk HPV DNA was 21.47%(916/4267)at the age of 19-74.Among them,the highest positive infection rate distributed in 20-29 year group(26.68%)and 30-39 year group(27.22%).Single high risk HPV DNA subtype infection rate was 62.82%(575/916),multiple high risk HPV DNA subtypes infection rate was 37.18%(341/916)(χ2=56.53,P0.01).Two(29.42%,100/341)and 3(25.22%,86/341)subtypes are generally more common subtype infection in multiple high-risk HPV DNA subtypes,the others are 4,5 and 6 high risk mixed infection.The highest infection rate of HPV subtypes are HPV-16(33.78%,309/916),-58(17.15%,157/916),-33(11.29%,103/916)和-18(10.75%,98/916)。②Cytology test results showed,a total of 2613 cases(61.24%,2613/4267)without cervical intraepithelial neoplasia(CIN),906 cases(21.23%,906/4267)were atypical-squamous cells of undetermined significance/glandular cells(ASCUS),494(11.57%,494/4267)were low-grade intraepithelial lesion(LSIL),237(5.55%,237/4267)were high-grade intraepithelial lesion(HSIL),17(0.41%,17/4267)were squamous cell carcinoma(SCC).Conclusion The infection rate of high risk HPV DNA in this study was high.The women with high-risk human papilloma virus infection and abnormal cytological test result should be followed-up regularly." @default.
- W2364084150 created "2016-06-24" @default.
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- W2364084150 date "2011-01-01" @default.
- W2364084150 modified "2023-09-23" @default.
- W2364084150 title "Study of High-Risk Human Papillomavirus Infection and Cytological Test Conditions Among Women With Gynecological-Surgery in Haiyang City" @default.
- W2364084150 hasPublicationYear "2011" @default.
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