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- W2364089658 abstract "Objective To observe the inhibitory effect of Baicalin on formation of the photoproduct in human skin fibroblasts induced by ultraviolet B(UVB) light.Methods Human skin fibroblasts were incubated with various concentrations of Baicalin(0-250μg/mL) for 24 hours.Immunohistochemistry and immune dot blot test(IDBT) was used to detect cyclobutane pyrimidine dimmers(CPDs) in DNA of human skin fibroblasts 30 minutes after 30mJ/cm2 UVB radiation and Baicalin intervention.The UV absorbance ability of Baicalin was detected by UV spectrophotometer.Results Baicalin could reduced CPDs formation 30 minutes after UVB radiation.Baicalin had a strong ability to absorb ultraviolet energy within UVA,UVB and UVC band.Conclusion Baicalin can inhibit the the formation of the photoproducts induced by UVB light in human skin fibroblasts.Baicalin is an effective UV protectant." @default.
- W2364089658 created "2016-06-24" @default.
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- W2364089658 date "2011-01-01" @default.
- W2364089658 modified "2023-09-23" @default.
- W2364089658 title "Inhibitory Effects of Baicalin on Formation of the Photoproduct in Human Skin Fibroblasts Induced by Ultraviolet B Light" @default.
- W2364089658 hasPublicationYear "2011" @default.
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