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- W2364116521 abstract "Objective To investigate the clinicopathological features, diagnosis,and differential diagnosis of sacrococcygeal yolk sac tumor. Methods The samples of nine patients with sacral yolk sac tumor were processed with clinical pathological analysis and immunohistochemical staining,and the references about this clinical data were reviewed.Results Eight cases were girls,and one case was boys,whose ages were from 16 months to 44 months. The mass in buttocks or sacral region was the main clinical manifestations. For histopathological examination,typical endodermal sinus structures,and adenoid,papillary and loose network structures were found. Immunohistochemistry showed the expression of AFP with different levels in nine cases,of which five cases were spotty expression,and four cases were strongly positive diffuse cytoplasm. The spotty expression of PLAP was showed in two cases. CK was strongly positive in eight cases,and one case was negative. CD30,HCG,EMA,CD15,and CD117 were not expressed in nine cases. Five cases were promptly performed with chemotherapy after they were diagnosed. While three cases were relapsed and transformed without chemotherapy in the result of death. One case lost follow-up. Conclusion Sacrococcygeal yolk sac tumor with highgrade malignancy,is sensitive to chemotherapy,and more commonly occurs in girls. Diagnosis of sacrococcygeal yolk sac tumor is mainly depended on morphology and immunohistochemical staining." @default.
- W2364116521 created "2016-06-24" @default.
- W2364116521 creator A5055311961 @default.
- W2364116521 date "2015-01-01" @default.
- W2364116521 modified "2023-09-25" @default.
- W2364116521 title "Sacrococcygeal yolk sac tumor: clinicopathologic analyses of 9 cases" @default.
- W2364116521 hasPublicationYear "2015" @default.
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