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- W2364133986 abstract "Objective:Previous studies have demonstrated that LRP16 is an estrogen-responsive gene,the expression level of which is tightly linked with proliferation and invasive growth of human breast cancer cells.To further explore the physiological function of LRP16,here,we transfected LRP16 targeting vector pBΔ16 into ES cells and screened the ES clone with inactive LRP16 gene.Methods:ES cells were screened with G418 and the homologously recombinant clone was identified from 100 clones by southern blot analysis.Results:There was an ES clone with targeting sequence homolougously inserted.Conclusion: A homologous recombinant was obtained.The study lays the foundations of preparing mouse models of LRP16 knockout." @default.
- W2364133986 created "2016-06-24" @default.
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- W2364133986 date "2006-01-01" @default.
- W2364133986 modified "2023-09-28" @default.
- W2364133986 title "Identification of homologously recombinant clone of ES cells for mouse LRP16 gene" @default.
- W2364133986 hasPublicationYear "2006" @default.
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