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- W2364135961 abstract "Objective:To investigate the IL-2 and IL-10 changes impact of treatment outcome in Graves disease(GD).Methods:From January 2007 to December 2008,72 cases of patients with GD in our hospital were detected IL-2 and IL-10 and thyroid hormone levels before and after treatment respectively,the relationship between the IL-2 and IL-10 level with prognosis was evaluated.Results:There are 21 cases of GD in patients with uncontrolled hyperthyroidism,35 cases with hyperthyroidism control,16 cases of early-onset hypothyroidism.The level of IL-2 in uncontrolled hyperthyroidism were the highest,followed by hyperthyroidism control,and in early-onset hypothyroidism were the lowest(P 0.05);IL-10 levels into the trend of anti-change(P0.05).After treatment,IL-2 increased in uncontrolled hyperthyroidism,in hyperthyroidism control,IL-2 was essentially the same,and in early-onset hypothyroidism,IL-2 decreased(P 0.05);IL-10 levels into the anti-change(P 0.05).IL-2/IL-10 was highest level in uncontrolled hyperthyroidism,followed by hyperthyroidism control,and in early-onset hypothyroidism was the lowest(P0.05);and the level of IL-2/IL-10 was the same before and after treatment(P0.05).Conclusion:The higher IL-2/IL-10 ratio shows more difficult for control hyperthyroidism,the lower IL-2/IL-10 ratio shows more easy to produce hypothyroidism;IL-2/IL-10 is a good predictor for GD treatment outcome." @default.
- W2364135961 created "2016-06-24" @default.
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- W2364135961 date "2010-01-01" @default.
- W2364135961 modified "2023-09-23" @default.
- W2364135961 title "Detecting IL-2 and IL-10 to predicate treatment outcome for Graves disease" @default.
- W2364135961 hasPublicationYear "2010" @default.
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