FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364136865> ?p ?o ?g. }

• W2364136865 abstract "Aim: To observe the effect of electroacupuncture (EA) on acute myocardial ischemia (AMI) induced changes of cardiac sympathetic discharges and the effects of some related receptors in the spinal cord. Methods: A total of 53 rabbits anesthetized with mixture solution of 25% urethane (420 mg/kg) and 1.5% chloralose (50 mg/kg) were used in this study. AMI was induced by occlusion of the ventricular branch of the left coronary artery. Discharges of the left cardiac sympathetic nerve were recorded by using a bipolar platinum electrode. Bilateral Ximen(PC 40) and Kongzhui(LU 6) were stimulated electrically by using an EA therapeutic apparatus or an electrical stimulator. DPDPE δ opiate receptor agonist, 20 nmol, 10 μL, n=8), Naltrindole Hydrochloride (δ opiate receptor antagonist, 20 nmol, 10 μL, n=8), DAP5 (NMDA receptor antagonist, 5 nmol, 10 μL, n=9) and CNQX (non NMDA receptor antagonist, 5 nmol, 10 μL, n=8) were respectively injected into the thoracic subarachnoid space of the spinal cord in different groups, followed by observing their effects on changes of sympathetic activity evoked by EA of the abovementioned acupoints. Results: ① After AMI, sympathetic discharges increased (200.56±79.89%) in 10 cases and decreased (-59.34 ±7.06%) in other 9 cases in comparison with their individual basal values. After EA of Ximen (PC 4) and Kongzhui(LU 6), AMI induced increase and decrease changes of the sympathetic activity were suppressed significantly, but the effect of EA of LU 6 was weaker than that of EA of PC 4. ② Following EA of PC 4 and LU 6, sympathetic discharges increased significantly in 2 and 4 cases, decreased apparently in 7 and 3 cases, and had no striking changes in 1 and 3 cases respectively. The mean reaction threshold of sympathetic activity after EA of PC 4 and LU 6 were 2.1±0.65 mA and 3.28±1.13 mA separately. ③ After pre treatment with DPDPE, the reaction threshold of the cardiac sympathetic activity to EA of PC 4 elevated significantly (35.89±6.12%); while after pre treatment with Naltrindole, this reaction threshold decreased considerably (84.88±26.58%). Following intrathecal injection of DAP5 (n=9) and CNQX (n=9) , the reaction thresholds of the cardiac sympathetic activity to EA of PC 4 increased obviously (142.06±60.27% and 112.54±28.58% separately). It suggests that spinal δ opioid receptor, NMDA and non NMDA receptors are involved in EA induced changes of sympathetic activity. Conclusion: ① EA could regulate AMI induced changes of cardiac sympathetic activity; and ② spinal δ opioid receptors, NMDA and non NMDA receptors participate in the effect of EA on the cardiac sympathetic activity." @default.
• W2364136865 created "2016-06-24" @default.
• W2364136865 creator A5005138075 @default.
• W2364136865 date "2003-01-01" @default.
• W2364136865 modified "2023-09-23" @default.
• W2364136865 title "EFFECT OF ELECTROACUPUNCTURE ON MYOCARDIAL ISCHEMIA INDUCED CHANGES OF CARDIAC SYMPATHETIC ACTIVITY AND INVOLVEMENT OF SPINIAL δ-OPIOID, NMDA-AND NON-NMDA RECEPTORS IN THE RABBIT" @default.
• W2364136865 hasPublicationYear "2003" @default.
• W2364136865 type Work @default.
• W2364136865 sameAs 2364136865 @default.
• W2364136865 citedByCount "0" @default.
• W2364136865 crossrefType "journal-article" @default.
• W2364136865 hasAuthorship W2364136865A5005138075 @default.
• W2364136865 hasConcept C126322002 @default.
• W2364136865 hasConcept C134018914 @default.
• W2364136865 hasConcept C142724271 @default.
• W2364136865 hasConcept C170493617 @default.
• W2364136865 hasConcept C204787440 @default.
• W2364136865 hasConcept C2776202274 @default.
• W2364136865 hasConcept C2776885963 @default.
• W2364136865 hasConcept C2777953665 @default.
• W2364136865 hasConcept C2778122271 @default.
• W2364136865 hasConcept C42219234 @default.
• W2364136865 hasConcept C56837625 @default.
• W2364136865 hasConcept C67018056 @default.
• W2364136865 hasConcept C71924100 @default.
• W2364136865 hasConceptScore W2364136865C126322002 @default.
• W2364136865 hasConceptScore W2364136865C134018914 @default.
• W2364136865 hasConceptScore W2364136865C142724271 @default.
• W2364136865 hasConceptScore W2364136865C170493617 @default.
• W2364136865 hasConceptScore W2364136865C204787440 @default.
• W2364136865 hasConceptScore W2364136865C2776202274 @default.
• W2364136865 hasConceptScore W2364136865C2776885963 @default.
• W2364136865 hasConceptScore W2364136865C2777953665 @default.
• W2364136865 hasConceptScore W2364136865C2778122271 @default.
• W2364136865 hasConceptScore W2364136865C42219234 @default.
• W2364136865 hasConceptScore W2364136865C56837625 @default.
• W2364136865 hasConceptScore W2364136865C67018056 @default.
• W2364136865 hasConceptScore W2364136865C71924100 @default.
• W2364136865 hasOpenAccess W2364136865 @default.
• W2364136865 hasRelatedWork W1986105132 @default.
• W2364136865 hasRelatedWork W2009089882 @default.
• W2364136865 hasRelatedWork W2011548206 @default.
• W2364136865 hasRelatedWork W2017330261 @default.
• W2364136865 hasRelatedWork W2019825175 @default.
• W2364136865 hasRelatedWork W2031502741 @default.
• W2364136865 hasRelatedWork W2043211942 @default.
• W2364136865 hasRelatedWork W2044853986 @default.
• W2364136865 hasRelatedWork W2067466761 @default.
• W2364136865 hasRelatedWork W2072655790 @default.
• W2364136865 hasRelatedWork W2126375543 @default.
• W2364136865 hasRelatedWork W2213690410 @default.
• W2364136865 hasRelatedWork W2357785533 @default.
• W2364136865 hasRelatedWork W2412108253 @default.
• W2364136865 hasRelatedWork W2413854296 @default.
• W2364136865 hasRelatedWork W2757971058 @default.
• W2364136865 hasRelatedWork W2989576747 @default.
• W2364136865 hasRelatedWork W3003639774 @default.
• W2364136865 hasRelatedWork W3141458501 @default.
• W2364136865 hasRelatedWork W417056568 @default.
• W2364136865 isParatext "false" @default.
• W2364136865 isRetracted "false" @default.
• W2364136865 magId "2364136865" @default.
• W2364136865 workType "article" @default.