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- W2364139263 abstract "Objective: To study the correlation of thermodose and death rate of mice and quantitative analysis of thermotolerance in whole body hyperthermia (WBH). Methods: NIH mice were used in our experiments. Death was the end point of the observation. Treatment temperature ranged from 40.5 to 43. Thermotolerance was induced with a prior-shock of 25 min at 41.5.Thermotolerance at 41.5 and 42 was measured at 24 hr.,72 hr. and 96 hr. after the challenge dose. Results: Time required to kill 50% mice were 40.81 min. at 41.5,22.52 min. at 42, 18.23 min. at 42.5and 13.78 at 43.Thermotolerance reached maximum at 24 hr. and decreased by 50% every 24 hrs, Maximal death rate was 40% at 41. Conclusions :Thermotolerance is induced after 2 hrs. at temperature41.5 during treatment. Thermotolerance is maximal at 24 hr. and decreased by about 50% every 24 hrs." @default.
- W2364139263 created "2016-06-24" @default.
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- W2364139263 date "1999-01-01" @default.
- W2364139263 modified "2023-09-25" @default.
- W2364139263 title "Thermotolerance of whole body hyperthermia in NIH mice" @default.
- W2364139263 hasPublicationYear "1999" @default.
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