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- W2364143412 abstract "Plasminogen activator inhibitor-1(PAI-1)is the main regulator of the fibrinolytic system. Recent researches find that the elevation of PAI-1 level is a core feature of metabolic syndrome, and has a close relationship with obesity, insulin resistance, type 2 diabetes, cardiovascular diseases, dyslipidemia and hypertension, and even may influence the accumulation of visceral fat. Therefore, direct inhibition of PAI-1 might not only provide a new therapeutic strategy for reducing cardiovascular risk, but also have beneficial effects on obesity, insulin resistance and type 2 diabetes." @default.
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- W2364143412 date "2006-01-01" @default.
- W2364143412 modified "2023-09-28" @default.
- W2364143412 title "Plasminogen activator inhibitor-1 and metabolic syndrome" @default.
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