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- W2364145281 abstract "Objective:Discuss to the influence of Buyuan Congnao Decoction(BCD) which is AD rat models recognize ability and the expression of apoptosis related protein Bax and Bcl-2 in rats'hippocampus and the possible protection mechanism of the Alzheimer's Disease(AD).Methods:To adopt IBO and Aβ 1-42 of the mixed solution injection to hippocampus establish AD rat models,and apply Morris water maze method to examine study and memory abilities on AD rat models,The expression of apoptosis related protein Bax and Bcl-2 in rats'hippocampus were studied by immunohistochemistry method.Results:BCD can improve AD big rat recognition ability,repress Bax expression and raise the expression of Bcl-2.Model set and normal set compared,recognize ability is descend,hippocampus of Bax expression increase,and Bcl-2 expression decrease;treatment set and model set compared,recognize ability is remarkable improvement,hippocampus of Bax expresses fall off,the expression of Bcl-2 is moved up.Conclusions:The protection function of BCD which to the AD rats' brain nerve cells is possible that strengthen expression to damaged hippocampus neuron Bcl-2,and decrease to Bax.Thus the study memory of the AD rat is improved." @default.
- W2364145281 created "2016-06-24" @default.
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- W2364145281 date "2011-01-01" @default.
- W2364145281 modified "2023-09-23" @default.
- W2364145281 title "Influence of the BCD to AD Big Rat's Praxiology and the Expression of Apoptosis Related Protein Bax and Bcl-2 in Rats'Hippocampus" @default.
- W2364145281 hasPublicationYear "2011" @default.
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