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- W2364153206 abstract "In order to explore the biocompatibility of nano-layered double hydroxides (nano-LDHs) with Hela cells, a single cell gel electrophoresis and H2DCF-DA fluorescent coloration assay were used to analyze the DNA damage and the change of reactive oxygen species (ROS) in Hela cells exposed to nano-LDHs. Results showed that, with the increase of concentrations of nano-LDHs (0~800μg·mL-1), the Tail DNA%, Tail Moment and ROS contents in Hela cells increased gradually; There were significant differences (p0.05, p0.01) in Tail DNA%, Tail Moment and ROS contents between the high concentration groups (200、400、 800μg·mL-1) and the control group, while no significant differences (p0.05) were found between the low concentration groups (50, 100μg·mL-1) and the control group. The above results suggested that the high concentration nano-LDHs (≥200μg·mL-1) could induce the DNA damage in Hela cells and the low concentration nano-LDHs (≤100μg·mL-1) had a good biocompatibility with Hela cells." @default.
- W2364153206 created "2016-06-24" @default.
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- W2364153206 date "2008-01-01" @default.
- W2364153206 modified "2023-09-27" @default.
- W2364153206 title "Study on Biocompatibility of Nano-Layered Double Hydroxides with Hela Cells" @default.
- W2364153206 hasPublicationYear "2008" @default.
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