Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364157574> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2364157574 abstract "The absorption kinetics of pramipexole(1) at different intestinal segments in rats and the influence of concentration and pH on the absorption kinetics were investigated with in situ perfusion.An HPLC method was developed to determine the concentrations of 1 in intestinal circulated fluid.The results showed that 1 can be absorbed in whole intestine.The absorption rate constants(Ka) at duodenum,colon,ileum and jejunum were 0.295 h-1,0.513 h-1,0.480 h-1 and 0.808 h-1,respectively.The absorptions in intestine were increased by the drug concentrations.The concentration of 1 and pH had no distinctive effect on the absorption kinetic.The absorption of 1 was in line with first-order kinetics with passive diffusion absorption mechanism.The absorption kinetics of stomach was obtained by the in situ perfusion method in rats.There is little absorption of 1 in stomach." @default.
- W2364157574 created "2016-06-24" @default.
- W2364157574 creator A5053619899 @default.
- W2364157574 date "2011-01-01" @default.
- W2364157574 modified "2023-09-25" @default.
- W2364157574 title "In situ Absorption Kinetics of Pramipexole in Rats Intestine" @default.
- W2364157574 hasPublicationYear "2011" @default.
- W2364157574 type Work @default.
- W2364157574 sameAs 2364157574 @default.
- W2364157574 citedByCount "0" @default.
- W2364157574 crossrefType "journal-article" @default.
- W2364157574 hasAuthorship W2364157574A5053619899 @default.
- W2364157574 hasConcept C121332964 @default.
- W2364157574 hasConcept C125287762 @default.
- W2364157574 hasConcept C126322002 @default.
- W2364157574 hasConcept C148898269 @default.
- W2364157574 hasConcept C159985019 @default.
- W2364157574 hasConcept C185592680 @default.
- W2364157574 hasConcept C192562407 @default.
- W2364157574 hasConcept C2776366702 @default.
- W2364157574 hasConcept C2776809568 @default.
- W2364157574 hasConcept C2777226302 @default.
- W2364157574 hasConcept C2777882243 @default.
- W2364157574 hasConcept C2779422922 @default.
- W2364157574 hasConcept C41625074 @default.
- W2364157574 hasConcept C43617362 @default.
- W2364157574 hasConcept C55493867 @default.
- W2364157574 hasConcept C62520636 @default.
- W2364157574 hasConcept C71924100 @default.
- W2364157574 hasConcept C99533885 @default.
- W2364157574 hasConceptScore W2364157574C121332964 @default.
- W2364157574 hasConceptScore W2364157574C125287762 @default.
- W2364157574 hasConceptScore W2364157574C126322002 @default.
- W2364157574 hasConceptScore W2364157574C148898269 @default.
- W2364157574 hasConceptScore W2364157574C159985019 @default.
- W2364157574 hasConceptScore W2364157574C185592680 @default.
- W2364157574 hasConceptScore W2364157574C192562407 @default.
- W2364157574 hasConceptScore W2364157574C2776366702 @default.
- W2364157574 hasConceptScore W2364157574C2776809568 @default.
- W2364157574 hasConceptScore W2364157574C2777226302 @default.
- W2364157574 hasConceptScore W2364157574C2777882243 @default.
- W2364157574 hasConceptScore W2364157574C2779422922 @default.
- W2364157574 hasConceptScore W2364157574C41625074 @default.
- W2364157574 hasConceptScore W2364157574C43617362 @default.
- W2364157574 hasConceptScore W2364157574C55493867 @default.
- W2364157574 hasConceptScore W2364157574C62520636 @default.
- W2364157574 hasConceptScore W2364157574C71924100 @default.
- W2364157574 hasConceptScore W2364157574C99533885 @default.
- W2364157574 hasLocation W23641575741 @default.
- W2364157574 hasOpenAccess W2364157574 @default.
- W2364157574 hasPrimaryLocation W23641575741 @default.
- W2364157574 hasRelatedWork W2348532665 @default.
- W2364157574 hasRelatedWork W2350052092 @default.
- W2364157574 hasRelatedWork W2350678588 @default.
- W2364157574 hasRelatedWork W2351730325 @default.
- W2364157574 hasRelatedWork W2352438883 @default.
- W2364157574 hasRelatedWork W2356161262 @default.
- W2364157574 hasRelatedWork W2360709243 @default.
- W2364157574 hasRelatedWork W2362583932 @default.
- W2364157574 hasRelatedWork W2368813321 @default.
- W2364157574 hasRelatedWork W2373339950 @default.
- W2364157574 hasRelatedWork W2374351649 @default.
- W2364157574 hasRelatedWork W2378012680 @default.
- W2364157574 hasRelatedWork W2381137677 @default.
- W2364157574 hasRelatedWork W2385334799 @default.
- W2364157574 hasRelatedWork W2385410193 @default.
- W2364157574 hasRelatedWork W2386401443 @default.
- W2364157574 hasRelatedWork W2389258846 @default.
- W2364157574 hasRelatedWork W2389566491 @default.
- W2364157574 hasRelatedWork W2392952579 @default.
- W2364157574 hasRelatedWork W3024177984 @default.
- W2364157574 isParatext "false" @default.
- W2364157574 isRetracted "false" @default.
- W2364157574 magId "2364157574" @default.
- W2364157574 workType "article" @default.