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- W2364162144 abstract "Objective To investigate and analyze the clinical effect of sevelamer hydrochloride combined with hemodialysis in the treatment of renal osteopathy. Methods 90 cases of patients with renal osteodystrophy in our hospital from June 2013 to June 2014 were selected and were randomly divided into control group A,control group B and observation group.The patients in control group A and control group B were respectively treated with sevelamer hydrochloride and hemodialysis.The patients in observation group were treated with the combination of sevelamer hydrochloride and hemodialysis.The clinical therapeutic effect,commonly used biochemical indicators before and after treatment and adverse reactions after treatment among three groups of patients was observed respectively. Results The levels of Ca2+ ,P3-,calcium-phosphorus product and PTH among three groups of patients didn't show obvious difference before treatment.The levels of Ca2+ among three groups of patients were increased after treatment,and the level of Ca2+ in observation group was significantly higher than that in control group A and B.The levels of P3-,calcium-phosphorus product and PTH were decreased among three groups of patients,and the levels of P3-,calcium-phosphorus product and PTH in observation group were significantly lower than that in control group A and B,with statistical difference(P0.05).Total clinical efficiencies in control group A,B and observation group were separately 70.00 %,60.00 % and 93.33%.The efficiency in observation group was significantly higher than that in control group A and B,with statistical difference(P0.05).The incidences of adverse reactions among three groups were separately 53.33%,56.67% and 10.00%.The incidence of adverse reaction in observation group was significantly lower than that in control group A and control group B,with statistical difference(P0.05). Conclusion The clinical effect of sevelamer hydrochloride combined with hemodialysis in the treatment of renal osteopathy shows an significant advantage than that of separately oral administration of sevelamer hydrochloride and hemodialysis.The combination of the two drugs is of high security.Therefore,the sevelamer hydrochloride combined with hemodialysis in the treatment of renal osteopathy is worthy of promotion in the clinical practice." @default.
- W2364162144 created "2016-06-24" @default.
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- W2364162144 date "2015-01-01" @default.
- W2364162144 modified "2023-09-25" @default.
- W2364162144 title "Clinical effect of sevelamer hydrochloride combined with hemodialysis in the treatment of renal osteopathy" @default.
- W2364162144 hasPublicationYear "2015" @default.
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