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- W2364163914 abstract "Purpose:The authors' aim was to measure the len gth of distal margin between the lower border of the tumor at different times in low anterior resection for rectal cancer and analyze their relations to prognos is. Methods:In 184 patients, who underwent low anterior resection, the distal margin of sample was measured at the time before resection (BRM), jus t after removing of the specimen (ARM), and after fixation (FM) of the same spec imen. Different distal margins in relation to survival and local recurrence were analyzed. Results:The distal margin of specimen shrank at different times of measurement. The shrinkage ratio was 71.7%, 60.1%, and 43.5% from BRM (mean= 4.6, SD=0.9) to ARM (mean=3.3, SD=1.1), ARM to FM (mean=2.0, SD=0.9), and BRM to FM respectively. The ARM was ≤ 2 cm and 2 cm in 36 (20%) and 148 (80%) patie nts respectively, and the FM was ≤ 1 cm and 1 cm in 42 (23%) and 142 (77%) pa tients respectively. Of the 12 patients (6.5%) who developed local recurrence, 4 patients had ARM of ≤ 2 cm and 8 patients had ARM of 2 cm. Survival analysis demonstrated that the overall survival and local recurrence was not significant ly different between patients with ARM of ≤ 2 cm and patients with that of 2 cm, and also between patients with FM of ≤ 1 cm and patients with that of 1 c m. Conclusions:The shrinkage of distal margin at different times s hould be considered in low anterior resection for rectal cancer. Our data sugges t that for patients with rectal cancer undergoing low anterior resection, distal margins ≤ 2 cm immediately measured just after resection of specimen do not se em to affect the outcome." @default.
- W2364163914 created "2016-06-24" @default.
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- W2364163914 date "2005-01-01" @default.
- W2364163914 modified "2023-09-27" @default.
- W2364163914 title "Analysis of distal margin in low anterior resection for rectal cancer and its effects on prognosis" @default.
- W2364163914 hasPublicationYear "2005" @default.
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