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- W2364165810 abstract "Objective To explore the clinical features and influential factors for the post-stroke sleep disorders in patients with incipient or mild stroke in the acute stage,and examine the effects of drug intervention for insomniacs post-stroke.MethodsTwo hundred and twenty-six patients with stroke were recruited.Pittsburgh Sleep Quality Index (PSQI),Nerve Function Deficit Score (NDS),Modified Barthel Index (MBI),Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) were used to evaluate sleep disorders of the enrolled patients.Sleep disorder was defined as PSQI scores were higher than 7.The types and features of sleep disorders in post-stroke patients were reviewed.Influential factors were differentially analyzed respect to the incidence of sleep disorders among different populations with stroke.The differences of scores evaluated by each scale were compared between patients with or without sleep disorders.Moreover,57 insomniacs with sleep disorders were further selected and evaluated with each and every scale,and the obtained scores were recorded pre-treatment (within 1 week post-stroke) and 2 weeks post-treatment and then compared.ResultsSleep disorders,which occurred in 99 out of 226 patients (43.8%),featured as hypersomnia in patients with hemorrhage stroke,whereas insomnia in patients with ischemic stroke.The incidence of sleep disorders in the patients with mild stroke in acute stage was closely associated with gender,age,stroke location,neurologic impairment,activity of daily living and mental status (with or without anxiety or depression).Severer neurologic impairment and depression and lower activity of daily living were found in the patients with sleep disorders compared to those without sleep disorders (P0.05).After early drug intervention,obvious amelioration was found in the post-stroke insomniacs on neurologic function,mental status,activity of daily living and sleep quality (P0.05).ConclusionsThe incidence of sleep disorders is higher in patients with primary and mild stroke at acute stage.The main factors influencing the incidence are gender,age,stroke site,extent of neurologic impairment,activity of daily living and mental status.Active therapy in acute stage of stroke may be beneficial to recovery of neurologic function and improvement of life quality." @default.
- W2364165810 created "2016-06-24" @default.
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- W2364165810 date "2010-01-01" @default.
- W2364165810 modified "2023-09-23" @default.
- W2364165810 title "Influential factors of sleep disorders in acute stage of mild stroke and efficacy analysis of drug intervention for insomniacs" @default.
- W2364165810 hasPublicationYear "2010" @default.
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