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- W2364169611 abstract "Objective To explore factors leading to the termination of antiretroviral therapy among AIDS patients who were receiving free treatment.Methods The data of antiretroviral therapy over the province were collected by the DataFax antiretro-viral therapy information searching system commonly used in China,and the cross-section survey method was adopted to classify systematically the factors leading to the termination of antiretroviral therapy among AIDS patients in Hubei province.Logistical regression analysis was also employed for the data of both deceased and surviving cases by using 1∶2-match case-control study.Results (1)There was an evident gender difference in the rate of antiretroviral therapy termination;(2)The primary factor leading to therapy termination was adverse reaction of the drug(56.74%);and the next was death(36.17%);(3)The main symptom of adverse reaction was abnormal liver function(52.50%);(4)The risk factor to death in the course of therapy was poor compliance,and failure to take bills regularly represented greater risk to the patients(P=0.0086,OR 95% CI is 1.165～2.852).The factors preventing death in the course of treatment included absence of side effect(P=0.0027,OR95% CI is 0.320～0.787),and immediate adoption of alternative drugs(P0.01,OR 95% CI is 0.262～0.636).Conclusion Education should be strengthened among AIDS patients to improve their compliance with treatment regime and a system to monitor the adverse reaction of antiretroviral drugs should be established so that alternative drugs could be used timely whenever side effect of one drug is identified.Only by adopting all these measures in a proper way,can the antiretroviral therapy be sustained." @default.
- W2364169611 created "2016-06-24" @default.
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- W2364169611 date "2006-01-01" @default.
- W2364169611 modified "2023-09-23" @default.
- W2364169611 title "Analysis of factors leading to the termination of AIDS antiretroviral therapy in Hubei Province" @default.
- W2364169611 hasPublicationYear "2006" @default.
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