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- W2364173264 abstract "To establish an HPLC method for the determination of content and related substances of Venlafaxine hydrochloride capsules.Agilent ZORBAX Eclipse XDB-C8 column(4.6 mm×250 mm,5 μm)was used and the mobile phase was phosphate buffer(pH 6.8)-acetonitrile-triethylamine(30∶70∶1),adjusted pH to 4.0 with phosphoric acid,The flow rate was 1.0 mL/min,the detection wavelength was at 230 nm.The venlafaxine hydrochloride and related substances could be baseline separated,and excipient didn't disturb the determination.The calibration curves for venlafaxine hydrochloride were linear over the range of 26.96~377.44 μg/mL(r=0.999 9).The detection limit was 53.6 ng/mL,The average recoveries were 99.1%,(n=9).This method is rapid,accurate sensitive and can be used for determination of the content and related substances of Venlafaxine hydrochloride capsules." @default.
- W2364173264 created "2016-06-24" @default.
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- W2364173264 date "2008-01-01" @default.
- W2364173264 modified "2023-09-24" @default.
- W2364173264 title "HPLC Method for Determination of Content and Related Substances of Venlafaxine hydrochloride capsules" @default.
- W2364173264 hasPublicationYear "2008" @default.
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