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- W2364174009 abstract "Objective Setting up one suitable cerebral ischemia animal model for seeking emergence and prevention of disease. Methods This research adopts the pairs of side common carotid artery (CCA) permanent ligature , pairs of side vertebra artery (VA) electricity congeal and pairs of side common carotid artery insert closing repeatedly, pairs of side common carotid artery (CCA) insert closing repeatedly and whole body hypotension three different cerebral ischemia model manufacture methods to process the rats, and then test Morris water maze in 15d, 30d, 60d, 90d after technique, analyzes each group's behavior study examination result using the SPSS11.0 statistics software, uses the average to average escape latency and the search strategy two targets by appraises the rat study memory ability. Results By the day 30 postchallenge, the group which VA electricity congealed and CCA insert closing repeatedly or the group which CCA insert closing repeatedly and whole body hypotension are the worst in study memory ability through the Morris water maze[The day 30 postchallenge, Average escape latency:(29.23±5.39)s,(30.03±8.84)s; the synthesis scores points: 766.2±173.55, 610.2±73.81]; In 30d~60d postchallenge, the group of CCA permanent ligature and the group of VA electricity congeal and CCA insert closing repeatedly are the worst[The day 60 postchallenge, Average escape latency:(18.56±4.15)s,(20.61±4.87)s; the synthesis scores points: 449.4±95.45, 437.4±80.22];60 days after ischemia,the group of CCA permanent ligature is the worst[The day 90 postchallenge, Average escape latency:(16.63±3.00)s; the synthesis scores points: 410.8±92.37].Conclusion These three methods in the influence of studying memory ability of the rat's are closely related to different ischemiatime, suited to the studying of the cerebral ischemia disease which induced in the different causes." @default.
- W2364174009 created "2016-06-24" @default.
- W2364174009 creator A5087296004 @default.
- W2364174009 date "2005-01-01" @default.
- W2364174009 modified "2023-09-24" @default.
- W2364174009 title "Influences of study and memory ability in rat following the different ways of cerebral ischemia" @default.
- W2364174009 hasPublicationYear "2005" @default.
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