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- W2364177907 abstract "OBJECTIVE To study the effects of Shuganwan (SHGW) on gastrointestinal motility in mice, gastric secretion in rats and analgesic effect in mouse. METHODS The effect on gastrointestinal motility was observed by using gastric emptying and small intestinal propulsion in mouse. The effect on gastric secretion in rats was studied with pylorus ligation. The analgesic effect was tested by the hot - plate test and writhing method. RESULTS SHGW markedly delayed gastric emptying in normal mouse and when gastric emptying and small intestinal propulsion was stimulated by neostigmine. SHGW faintly strengthed the effect of atropine on gastrointestinal motility. SHGW significantly inhibited the secretoin of gastric acid and pepsin and promoted the secretion of gastric mucus. SHGW enhanced hot pain threshold and decreased the number of twisting body in mice. CONCLUSIONS Shuganwan can delay gastric emptying, inhibit the secretion of gastric acid and pepsin and promote the secretion of gastric mucus; and has analgesic action in experimental studies." @default.
- W2364177907 created "2016-06-24" @default.
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- W2364177907 date "2003-01-01" @default.
- W2364177907 modified "2023-09-23" @default.
- W2364177907 title "Experimental study on gastrointestinal function and analgesic effect of Shuganwan" @default.
- W2364177907 hasPublicationYear "2003" @default.
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