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- W2364181552 abstract "AIM: To investigate the effects of external counterpulsation (.ECP) on the hemodynarmcs indexes and en-dothelin- 1 (ET-1) in myocardial ischemia canines. METHODS: Nineteen health dogs were randomly divided into controls, ischemia and ECP groups. The blood pressure, left ventricular systolic and diastolic pressure, +dp/dtmax and -dp/dtmax, brachiocephalic trunk blood flow were recorded. Plasma and myocardium ET - 1 levels were determined by radioimmunoassay. RESULTS: 60 minutes after left anterior descending oi coronary artery ligation, compared with controls, the blood pressure decreased greatly, left ventricular systolic and diastolic function declined, brachiocephalic trunk blood flow reduced, but plasma ET ?1 levels were increased significantly in ischemia and ECP groups (P0.05). After 2 h ECP treatment, compared with ischemia, blood pressure increased, left ventricular systolic and diastolic function improved, brachiocephalic trunk blood flow raised, but the plasma and myocardium ET- 1 levels were decreased in ECP group (P0.05). CONCLUSION: The results suggest that ECP improves the hemodynamics indexes in rnyocardial ischemia canine, and ET- 1 may play an important role." @default.
- W2364181552 created "2016-06-24" @default.
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- W2364181552 date "2005-01-01" @default.
- W2364181552 modified "2023-09-25" @default.
- W2364181552 title "Effects of external counterpulsation on the hemodynamics and endothelin-1 in myocardial ischemia canines" @default.
- W2364181552 hasPublicationYear "2005" @default.
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