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- W2364190227 abstract "Objective To study the influence of bisoprolol on early or long-term hemodynamic and exercise capacity with chronic heart failure(CHF).Methods 100 CHF patients were divided into two groups,the contrast and the bisoprolol group,50 cases respectively(NYHA grading Ⅱ-Ⅳ),and were gone in the random parallel contrast blind studied duration one year.Distance of 6 minutes and maximum exercise volume of consuming Oxgen(VO 2MAX )were detected before researched and again measured the baseline of hemodynamic,then the contrast group administered stable dosage deuretic、digoxin and ACEI orally,the bisoprolol group administered bisoperolol orally,1.25mg per day again,and reached the target dosage 10mg per day least 6～8 week until completing hemodynamic and exercise test in one year.Results The bisoprolol group early hemodynamic effect worsens,surronding vessel resistarce(SVR) increase,Left ventricular ejection fraction(LVEF) decrease(P0.05);The long-term hemodynamic of two groups were clear improvement(P0.05),difference was notable between the two groups.cardic out put(CO),cardiac index(CI)、LVEF,VO 2MAX and the distance of 6 minutes were significantly improved(P0.05).Conclusion The early hemodynamic of bisoprolol effect worsens,but the long-term hemodynamic and exercise capacity were significantly improved." @default.
- W2364190227 created "2016-06-24" @default.
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- W2364190227 date "2004-01-01" @default.
- W2364190227 modified "2023-09-28" @default.
- W2364190227 title "Influence of Bisoprolol on Hemodynamic and Exercise Capacity with Chronic Heart Failure" @default.
- W2364190227 hasPublicationYear "2004" @default.
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