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- W2364197816 abstract "Objective To prepare the pregabalin gastric floating sustained-release tablets and investigate the drug release by UV. Methods Pregabalin was used as a model drug with Polyox WSR 303, Polyox WSR N-60 K, HPMC K15 M and sodium alginate as matrix materials. The content of pregabalin was determined by ultraviolet spectrophotometry at 365 nm and accumulative release amount was calculated. Results The tablets showed a good sustained-release and continuous floating property with Polyox WSR 303 250 mg/tablet, Polyox WSR N-60 K 250 mg/tablet, sodium alginate150 mg/tablet. Conclusions Floating state of pregabalin gastric floating sustained-release tablets was maintained during the whole release process, and sustained-release properties was achieved." @default.
- W2364197816 created "2016-06-24" @default.
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- W2364197816 date "2015-01-01" @default.
- W2364197816 modified "2023-09-26" @default.
- W2364197816 title "Preparation and in vitro release of pregabalin gastric floating sustained-release tablets" @default.
- W2364197816 hasPublicationYear "2015" @default.
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