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- W2364199803 abstract "Objective To observe the effect of adenosine agonist on extracellular calcium after spinal cord injury (SCI) in rats, and to explore the protective mechanism of adenosine on SCI.Methods Moderate spinal cord injury of T13 was made by using ventral compression model in rats. The extracellular fluid was collected by using microdialysis, and the calcium was measured at preinjury and postinjury by using atomic absorption spectrophotometer. In treatment group, 2－ chroloadenosine (2－ CADO), a nonspecific receptor agonist, was given by intrathacal injection 15 min before injury. While in control group, the same volumn of saline was given.Results The extracellular calcium decreased significantly after SCI. Compared with control group, treatment with 2－ CADO improved the extracellular calcium significantly. Conclusion Adenosine exerted its neuroprotective role by inhibiting influx of extracellular calcium." @default.
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- W2364199803 date "2001-01-01" @default.
- W2364199803 modified "2023-09-26" @default.
- W2364199803 title "Subarachdonic 2－ chroloadenosine injection on extracellaler Ca2＋ after spinac injury" @default.
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