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- W2364201540 abstract "Model organisms play critical roles in life science. At present, lack of mature model systems is one of the major bottlenecks that hinder the study of the biosynthesis of natural medicines. Ganoderma lucidum is one of the most widely studied medicinal organisms and has the general features of model organisms: short life cycle, ability to produce large number of progenies, small genome size, easy to culture and genetically transform, and no harm for human being and the environment. In addition, G. lucidum involves multiple biosynthetic pathways of secondary metabolites, making it an ideal model to study the biosynthesis of secondary metabolites and their regulations. Recently, the elucidation of the chromosome-level genome has laid the solid foundation for further application of G. lucidum as a medicinal model organism. G. lucidum is supposed to play important roles in the study on the diversity of secondary metabolites, development of medicinal fungi and synthetic biology of natural medicines. In addition, the proposal of G. lucidum as a medicinal model fungus will greatly contribute to introducing state-of-the-art technologies and strategies of modern life sciences into the study of medicinal organisms and uncovering the common mechanisms and principles in the biosynthesis of secondary metabolites, thus paving the way for the construction of effective and controllable biosynthetic platform of natural medicines." @default.
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- W2364201540 date "2013-06-01" @default.
- W2364201540 modified "2023-09-27" @default.
- W2364201540 title "<italic>Ganoderma lucidum</italic>: an Emerging Medicinal Model Fungus for Study of the Biosynthesis of Natural Medicines" @default.
- W2364201540 doi "https://doi.org/10.1360/052012-425" @default.
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