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- W2364211441 abstract "Objective To explore the clinical value of cholic acid and partial serum biochemical parameters in gestational intrahepatic cholestasis of pregnancy(ICP).Methods The liver function and serum lipids levels of 280 patients with ICP in advanced gestation and 90 normal pregnant women were determined and compared.The ICP cases were divided into mild,medium,and highly increased group according to the levels of TBA,AST and ALT.Ninety women with normal pregnancy were sampled as the control.The rate of Caesarean birth and neonatal outcomes of the four groups were analyzed.Results Compared with normal cases,the Caesarean birth rate was greatly increased in ICP cases(P 0.05).The incidences of in utero meconium passage,preterm delivery,low birth weight infant and neonatal asphyxia were higher in TBA,AST and ALT highly increased ICP patients than those in other groups(P 0.05),and higher in TBA,AST and ALT medium increased ICP patients than those in normal group(P 0.05).Conclusion The increased ALT and AST levels following the increase of cholic acid in patients with ICP may indicate adverse outcomes in neonates." @default.
- W2364211441 created "2016-06-24" @default.
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- W2364211441 date "2009-01-01" @default.
- W2364211441 modified "2023-09-23" @default.
- W2364211441 title "The clinical significance of cholic acid and partial biochemical parameters in gestational intrahepatic cholestasis of pregnancy" @default.
- W2364211441 hasPublicationYear "2009" @default.
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