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- W2364216936 abstract "Objective To explore the relationship of carotid artery intima-media thickness(IMT)with lipid levels and inflammatory factors in patients with subclinical atherosclerosis(SAS).Methods Eighty-eight patients with SAS were divided into IMT thickening group(n=35)and plaque group(n=53)according to the IMT,and another 88 healthy volunteers with normal endometrium were as controls(control group).The levels of triacylglycerol,total cholesterol,high density lipoprotein-cholesterol,low density lipoprotein-cholesterol(LDL-C),high sensitivity C-reactive protein(hsCRP),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)were detected and compared among three groups.And the differences of lipid level were compared among different hs-CRP levels for risk stratification in SAS patients.Results The levels of LDL-C,hs-CRP,IL-6and TNF-αwere(3.98±0.30)mmol/L,(2.85±0.20)μg/mL,(52.25±8.54)ng/L and(46.15±6.32)ng/L in IMT thickening group,and(4.15±0.10)mmol/L,(3.50±0.20)mg/L,(125.35±10.30)ng/L and(115.28±8.50)ng/L in plaque group,higher than those in control group((3.56±0.20)mmol/L,(0.57±0.10)mg/L,(20.56±5.75)ng/L,(18.32±3.25)ng/L)(P0.05).The levels of hs-CRP,IL-6and TNF-αwere higher in plaque group than those in IMT thickening group(P0.05),and there was no significant difference in LDL-C level between two groups(P0.05).The TC and LDL-C levels were higher in high-risk hs-CRP level patients((53.87±2.27),(4.46±0.44)mmol/L)than those in medium-risk hs-CRP level patients((43.65±2.80),(3.56±0.18)mmol/L)(P0.05).Conclusion Carotid IMT is correlated with LDL-C,hs-CRP,IL-6and TNF-αlevels,and LDL-C continuously increases with the increase of hs-CRP risk level." @default.
- W2364216936 created "2016-06-24" @default.
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- W2364216936 date "2014-01-01" @default.
- W2364216936 modified "2023-09-26" @default.
- W2364216936 title "Relationship of carotid intima-media thickness with blood lipid level and inflammatory factors in patients with subclinical atherosclerosis" @default.
- W2364216936 hasPublicationYear "2014" @default.
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