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- W2364220344 abstract "Objective To study the effects of serum IGF-1,TNF-α,and IL-8 on bone metabolize in male liver cirrhosis.Methods 90 male patients with hepatic cirrhosis were divided into 2 groups,osteoporosis(OP) group and non-osteoporosis(NOP) group.50 healthy subjects severd as controls serum levels of IGF-I,TNF-α,IL-8,osteocalin(BGP) and the bone mineral density(BMD) were mearured in these group.Results The levels of IGF-1,BGP,and BMD were lower in OP group than NOP group(P0.001)and controls(P0.001).The levels of TNF-α,IL-8 were higher in OP group than NOP group(P0.001)and controls(P0.001).The levels of IGF-1 were positively correlated with BGP and BMD(r=0.388、0.347,P0.05),and TNF-α,IL-8 negatively correlated with them(r=-0.484、-0.627,P0.05;r=-0.457、-0.595,P0.05).Conclusion The decreased levels of IGF-1 and increased levels of TNF-α,IL-8 may be important factors in causing osteoporosis in patients with liver cirrhosis." @default.
- W2364220344 created "2016-06-24" @default.
- W2364220344 creator A5086132892 @default.
- W2364220344 date "2009-01-01" @default.
- W2364220344 modified "2023-09-26" @default.
- W2364220344 title "Effects of Serum Insulin-like Growth Factor-1(IGF-1),Tumer Necrosis Factor(TNF-α),andIterleukin-8(IL-8) on Bone Metabolize in Male Patients with Liver Cirrhosis" @default.
- W2364220344 hasPublicationYear "2009" @default.
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