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- W2364225277 abstract "Objective To investigate survivin protein and risk factors in non-small cell colorectal cancer with a systematic review.Methods The published studies were searched in the Cochrane Libtary(Issue 1,2011),Pubmed and CNKI databases and other relevant journals were also handsearched.Then the quality of the included trials was assessed and meta-analysis was performed by Stata 11.0 software.Results As for the positive rate of survivin expression,significant differences were tested between colorectal cancer vs.normal tissues(OR=50.77,95%CI=22.69-113.62,P0.05).No significant difference was tested between sex,age,tumor location,tumor length,dukes stage,lymph node metastasis,histologic subtype and the overall survival time(P0.05) respectively.There were significant differences between recurrence or metastasis vs.non-recurrence or metastasis(P0.05).Survivin expression was positively correlated with Bcl-2(r=0.313,P0.01).Conclusion Survivin expression increased recurrence or metastasis of coloreactal cancer,and meanwhile substantiaI correlation was confirmed between survivin and Bcl-2." @default.
- W2364225277 created "2016-06-24" @default.
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- W2364225277 date "2012-01-01" @default.
- W2364225277 modified "2023-09-24" @default.
- W2364225277 title "Clinicopathological Significance of Survivin Expression and Colorectal Cancer:a Meta Analysis" @default.
- W2364225277 hasPublicationYear "2012" @default.
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