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- W2364225788 abstract "Objective To investigate the correlation between histological grade aod expressions of estrogen receptor(ER),progesterone receptor(PR),CerBb-2 and p53,and lympha node metastasis of breast cancer.Methods The expressions of ER,PR,CerBb-2 and p53 in 187 cases breast cancer were detected by immunohistochemical method;Histological grade were detected by modified Nottingham of Bloom-Richardson system.Results There was no significant difference in positive expression rates of ER,PR and p53 among grade Ⅰ,Ⅱand Ⅲ(P0.05),but the ezpression of CerBb-2 increased with the rise of histological grade(P0.05).The expressions of CerBb-2(-) and p53(-) were higher than those of CerBb-2(+) and p53(+) in ER(+) in breast cancer tissue of ER(+) and PR(+)(P0.05).There was no obvious correlation between lympha node metastasis and histological grade of breast cancer tissue.Conclusion The expressions of ER,PR and p53 do not obviously change with increase of histological grade in breast cancer;but the expression of CerBb-2 does.The expressions of CerBb-2 and p53 are negatively correlated with ER expression;The lympha node metastasis is of no obvious correlation with histological grade of breast cancer." @default.
- W2364225788 created "2016-06-24" @default.
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- W2364225788 date "2008-01-01" @default.
- W2364225788 modified "2023-09-27" @default.
- W2364225788 title "Relation of Histological Grade with Expressions of Estrogen Receptor,Progesterone Receptor,CerBb-2 and p53 and Lympha Node Metastasis of Breast Cancer" @default.
- W2364225788 hasPublicationYear "2008" @default.
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