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- W2364226178 abstract "Objective: To investigate the acute toxicity of Glaucocalyxin A in mice and evaluate the safety,to provide the theoretic foundation for development of new medicine and clinical application.Methods: Aral administration and peritoneal injection were applied for the drug delivery.The mortality rates of different dosage of Glaucocalyxin A were observed and the LD50 was determined by Bliss assay.Results: The MTD of Glaucocalyxin A is 2.0 g·kg-1·d-1.The LD50 of Glaucocalyxin A has not been determined by Aral administration.The dosage of LD50 of Glaucocalyxin A by peritoneal injection was 168 mg/kg body weight in mice.The 95 % reliable limit is 149 mg/kg-188 mg/kg.Conclusion: Glaucocalyxin A is a low toxic drug with high safety." @default.
- W2364226178 created "2016-06-24" @default.
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- W2364226178 date "2013-01-01" @default.
- W2364226178 modified "2023-09-23" @default.
- W2364226178 title "Acute Toxicity of Glaucocalyxin A" @default.
- W2364226178 hasPublicationYear "2013" @default.
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