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- W2364226708 abstract "[Objective] To study bcl-2 and bax gene expression and related factors in severe pneumonia. [Methods] The staphylococcus aureus peumonia model of 30 Wistar rats was established and other 20 as control group. bcl-2, bax gene expression and cell apoptosis myocardial histopathologic score cardiac function and serum level of BNP were examed. [Results] The bcl-2 and bax gene expression were elevated in pneumonia with cardiac dysfunction. bcl-2 and bax gene expression was positively related to myocardial histopathologic score cardiomyocye apoptosis and serum BNP. bax gene expression was negatively related to heart function. The relation between indexes metioned above and gene expression is closer in bax than in bcl-2. [Conclusions] Severe pneumonia can be complicated with heart failure. The mechamism is related to overexpression of bcl-2 and bax gene." @default.
- W2364226708 created "2016-06-24" @default.
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- W2364226708 date "2006-01-01" @default.
- W2364226708 modified "2023-09-24" @default.
- W2364226708 title "Experimental research of the changes and related factors of the bcl-2 and bax gene expression in myocardium of severe pneumonia" @default.
- W2364226708 hasPublicationYear "2006" @default.
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