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- W2364241359 abstract "Objective To investigate the new methods of allogenic peripheral blood hematopoietic stem cells with bone marrow transplantation for leukemic patients.Methods 23 patients,9 patients were in HLA matched and 14 patients were in HLA1 to 3 loci mismatched.After conditioning,patients received GSF primed bone marrow with peripheral blood stem cells transplantation,graft-versus-host disease(GVHD)prophylaxis consisted of cyclosporine A,mycophenolate mofetil,and short course methotrexate.Results Engraftment failed in one patient.22 patients achieved full engraftment.The incidence of grades Ⅱ～ Ⅳacute GVHD was zero in HLA matched patients and was 46.2 % in HLA mismatched patients,13 patients developed chronic GVHD among 20 evaluable patients,cumulative incidence of cGVHD was 65 %,extensive type existed in 5 patients.follow-up lasted 6～32 months,1 year probabilities of disease-free survival was 86.6 %.Conclusion CSF primed bone marrow with peripheral blood stem cells transplantation is feasible and safe in HLA matched and mismatched transplantation for leukemic patients." @default.
- W2364241359 created "2016-06-24" @default.
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- W2364241359 date "2006-01-01" @default.
- W2364241359 modified "2023-09-24" @default.
- W2364241359 title "The clinical investigation of allogenic peripheral blood hematopoietic stem cells with bone marrow transplantation for leukemic patients" @default.
- W2364241359 hasPublicationYear "2006" @default.
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