Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364253255> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2364253255 abstract "The interaction of the five novel bis-naphthalimide derivatives(DN2-DN6) linked by methyl-isothiourea cation with DNA is investigated by UV absorption spectra,fluorescence spectra and circular dichroism(CD) spectra.The experimental results from UV absorption spectra show that when DNA is added,the hypochromic effect and faint red shift are observed in the absorption peak of DN2-DN6,and the longer the linker is,the more obvious the hypochromic effect is.The fluorescence of the compounds can be strongly quenched by DNA.The binding constants between DN3-DN6 and DNA increase with the alkyl chain’s extension,they are 1.18×105,1.36×105,1.67×105,2.32×105 L/mol,respectively.The compounds can free the acridine orange which intercalates into DNA base pairs,and the force becomes stronger with the linker’s extension.The CD spectrum results show that the double helix structure of DNA comes forth base stacking and unwinding locally,and the degree of base stacking is positively correlated with the length of alkyl chain.All experimental results show that DN2-DN6 bound to DNA by the intercalating binding mode and the order of intensity is DN6DN5DN4DN3DN2." @default.
- W2364253255 created "2016-06-24" @default.
- W2364253255 creator A5046595961 @default.
- W2364253255 date "2013-01-01" @default.
- W2364253255 modified "2023-09-23" @default.
- W2364253255 title "Research on interaction of novel bis-naphthalimide derivatives with DNA" @default.
- W2364253255 hasPublicationYear "2013" @default.
- W2364253255 type Work @default.
- W2364253255 sameAs 2364253255 @default.
- W2364253255 citedByCount "0" @default.
- W2364253255 crossrefType "journal-article" @default.
- W2364253255 hasAuthorship W2364253255A5046595961 @default.
- W2364253255 hasConcept C111919701 @default.
- W2364253255 hasConcept C119824511 @default.
- W2364253255 hasConcept C121332964 @default.
- W2364253255 hasConcept C133571119 @default.
- W2364253255 hasConcept C137824038 @default.
- W2364253255 hasConcept C178790620 @default.
- W2364253255 hasConcept C185581394 @default.
- W2364253255 hasConcept C185592680 @default.
- W2364253255 hasConcept C190283241 @default.
- W2364253255 hasConcept C2779102032 @default.
- W2364253255 hasConcept C2780263894 @default.
- W2364253255 hasConcept C2780557392 @default.
- W2364253255 hasConcept C33347731 @default.
- W2364253255 hasConcept C41008148 @default.
- W2364253255 hasConcept C552990157 @default.
- W2364253255 hasConcept C55493867 @default.
- W2364253255 hasConcept C62520636 @default.
- W2364253255 hasConcept C71240020 @default.
- W2364253255 hasConcept C75473681 @default.
- W2364253255 hasConcept C8010536 @default.
- W2364253255 hasConcept C91881484 @default.
- W2364253255 hasConceptScore W2364253255C111919701 @default.
- W2364253255 hasConceptScore W2364253255C119824511 @default.
- W2364253255 hasConceptScore W2364253255C121332964 @default.
- W2364253255 hasConceptScore W2364253255C133571119 @default.
- W2364253255 hasConceptScore W2364253255C137824038 @default.
- W2364253255 hasConceptScore W2364253255C178790620 @default.
- W2364253255 hasConceptScore W2364253255C185581394 @default.
- W2364253255 hasConceptScore W2364253255C185592680 @default.
- W2364253255 hasConceptScore W2364253255C190283241 @default.
- W2364253255 hasConceptScore W2364253255C2779102032 @default.
- W2364253255 hasConceptScore W2364253255C2780263894 @default.
- W2364253255 hasConceptScore W2364253255C2780557392 @default.
- W2364253255 hasConceptScore W2364253255C33347731 @default.
- W2364253255 hasConceptScore W2364253255C41008148 @default.
- W2364253255 hasConceptScore W2364253255C552990157 @default.
- W2364253255 hasConceptScore W2364253255C55493867 @default.
- W2364253255 hasConceptScore W2364253255C62520636 @default.
- W2364253255 hasConceptScore W2364253255C71240020 @default.
- W2364253255 hasConceptScore W2364253255C75473681 @default.
- W2364253255 hasConceptScore W2364253255C8010536 @default.
- W2364253255 hasConceptScore W2364253255C91881484 @default.
- W2364253255 hasLocation W23642532551 @default.
- W2364253255 hasOpenAccess W2364253255 @default.
- W2364253255 hasPrimaryLocation W23642532551 @default.
- W2364253255 hasRelatedWork W1597661332 @default.
- W2364253255 hasRelatedWork W1972201740 @default.
- W2364253255 hasRelatedWork W1978245859 @default.
- W2364253255 hasRelatedWork W1978504593 @default.
- W2364253255 hasRelatedWork W1980554015 @default.
- W2364253255 hasRelatedWork W1982382719 @default.
- W2364253255 hasRelatedWork W1995751415 @default.
- W2364253255 hasRelatedWork W1998942800 @default.
- W2364253255 hasRelatedWork W2012002884 @default.
- W2364253255 hasRelatedWork W2038692304 @default.
- W2364253255 hasRelatedWork W2044432299 @default.
- W2364253255 hasRelatedWork W2048049369 @default.
- W2364253255 hasRelatedWork W2056161950 @default.
- W2364253255 hasRelatedWork W2089852333 @default.
- W2364253255 hasRelatedWork W2114268635 @default.
- W2364253255 hasRelatedWork W2144389579 @default.
- W2364253255 hasRelatedWork W2147974296 @default.
- W2364253255 hasRelatedWork W2158519162 @default.
- W2364253255 hasRelatedWork W2164162624 @default.
- W2364253255 hasRelatedWork W2393151637 @default.
- W2364253255 isParatext "false" @default.
- W2364253255 isRetracted "false" @default.
- W2364253255 magId "2364253255" @default.
- W2364253255 workType "article" @default.