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- W2364260858 abstract "In order to figure out the effects of OM-APS(oxymatrine-astragalus polysaccharide) compound and their components on immune response of ND(newcastle disease) vaccine,six hundred and sixty 14-day-old non-immunized Roman cocks were randomly divided into 11 groups.Groups 1 to 9 were treated with OM-APS,OM and APS at high dose,medium dose,and low dose,respectively,and group 10 was treated with vaccine and group 11 was blank control.Groups 1 to 10 were inoculated with NDV-IV vaccine through intraocular-nasal route,repeated vaccination at day 28.At the same time of the first vaccination,the chickens in groups 1 to 9 were given the compounds through oral administration,and the chickens in group 1 and blank control group were given physiological saline,once a day for three days.On days 14,21,28,35 and 42,peripheral T lymphocyte proliferations and serum antibody titers were determined by MTT method and β-microscopic method respectively.On days 14,28 and 42,concentrations of IL-2 and IFN-γ of serum were determined by double antibody sandwich ELISA method.Tymphocyte proliferation,antibody titer and cytokines of chickens in the groups treated with high-and medium-dose of OM-APS,OM and APS were obviously higher than those in vaccine control group.At same ages of chickens,OM-APS performed better than OM and APS improving immune response to NDV-IV vaccine in chicken.It was indicated that the immunity of newcastle disease vaccine could be improved by OM-APS compound." @default.
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- W2364260858 date "2013-01-01" @default.
- W2364260858 modified "2023-09-23" @default.
- W2364260858 title "Effects of oxymatrine-astragalus polysaccharide compound and their components on immune response to newcastle disease vaccine in chicken" @default.
- W2364260858 hasPublicationYear "2013" @default.
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