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- W2364263706 abstract "Objective:To compare the differences of perioperative C-reactive protein (CRP),interleukin-6(IL-6),IL-10 and visceral proteins in laparoscopic and open radical resection of colorectal carcinoma for aged patients.Methods:According to patients' choice,laparoscopic (n=20) and open (n=21) radical resection of colorectal carcinoma were performed.There were no significantly statistical difference in age,sex and BMI of patients in 2 groups.The stress index of the 2 groups:IL-6,IL-10,CRP and visceral protein which included prealbumin(PRE),transferrin(TRF) and retinal-binding protein(RbP) were assayed preoperatively and at the 6h,1st,2nd and 3rd day postoperatively.Results:CRP levels in both groups increased at the 1st,2nd and 3rd day postoperatively compared to the preoperative period(P0.01)and reached the peak level at the 2nd day postoperatively,the response in the laparoscopic group was much less (P0.01).The plasma levels of IL-6 and IL-10 were significantly increased after the operation in both groups.However,it was lower in the laparoscopic group(P0.01).The increasing time of IL-10 was shorter than IL-6.The levels of PRE,TRF and RbP were considerably decreased after operation in both groups (P0.01),but there was no difference at the 1st and 2nd day (P0.05).All levels of the four proteins in the laparoscopic group were significantly higher than those in the open group at the 3rd day postoperatively (P0.01).Conclusions:According to the consequence of postoperative stress level and visceral proteins,laparoscopic radical resection of colorectal carcinoma results in less prominent stress response and trauma compared to open surgery in aged patient and it benefits the restoration of visceral proteins,which are strong supports for the minimally invasive surgery." @default.
- W2364263706 created "2016-06-24" @default.
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- W2364263706 date "2010-01-01" @default.
- W2364263706 modified "2023-09-26" @default.
- W2364263706 title "Operative stress response and visceral proteins after laparoscopic radical resection of colorectal carcinoma of aged patient" @default.
- W2364263706 hasPublicationYear "2010" @default.
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